Medical Animation: Osteoporosis Mechanism of Disease
Created for Biopharmaceutical client
Sclerostin, a Wnt antagonist, is produced when there is decreased load on bone and decreased estrogen during menopause. Sclerostin molecule floating in bone cellular environment. © 2016. All rights reserved.
Cross section view of osteoporotic bone structure in comparison with normal bone showing reduced thickness of both compact and spongy (trabecular) bone. Structural integrity of bone is compromised in osteoporotic bone which can result in low-impact fractures. © 2016. All rights reserved.
Trabecula in bone cellular environment with osteoblasts and osteoclasts present. The osteoblasts contribute to the formation of new bone, while osteoclasts are responsible for bone resorbtion. © 2016. All rights reserved.
3D patient render. Older woman walking down the street, trips on a crack in the sidewalk. Due to fragility in her bones from osteoporosis she endures a fracture. © 2016. All rights reserved.
The project
We created this mechanism of disease (MOD) 3D animation to educate healthcare providers on the molecular pathways underlying osteoporosis. Sclerostin is one of many factors that affects the downregulation of osteoblasts and overactivity of osteoclasts. The resulting imbalance can lead to fragility fractures in patients with osteoporosis. This MOD medical animation was paired with Rethink Osteoporosis, an interactive augmented reality experience we developed to provide an engaging way to learn about osteoporosis-related fragility fractures at our client’s congress exhibit booth.
Created for
Biopharmaceutical client
