Medical Animation: The Science of Hepatalin
Created for Scimar Ltd.
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Overview of hepatalin, its role in nutrient partitioning, and potential impact on type 2 diabetes care and prevention. The factory metaphor shows the interconnected systems involved in digestion and the downstream effects of changing just one signal. Viewers can easily see how hepatalin levels greatly impact nutrient partitioning to fat and muscle cells, and understand the consequences to a patient's health. © 2021 SciMar Ltd.
Overview of hepatalin, its role in nutrient partitioning, and potential impact on type 2 diabetes care and prevention. The factory metaphor shows the interconnected systems involved in digestion and the downstream effects of changing just one signal. Viewers can easily see how hepatalin levels greatly impact nutrient partitioning to fat and muscle cells, and understand the consequences to a patient's health. © 2021 SciMar Ltd.
Overview of hepatalin, its role in nutrient partitioning, and potential impact on type 2 diabetes care and prevention. The factory metaphor shows the interconnected systems involved in digestion and the downstream effects of changing just one signal. Viewers can easily see how hepatalin levels greatly impact nutrient partitioning to fat and muscle cells, and understand the consequences to a patient's health. © 2021 SciMar Ltd.
Overview of hepatalin, its role in nutrient partitioning, and potential impact on type 2 diabetes care and prevention. The factory metaphor shows the interconnected systems involved in digestion and the downstream effects of changing just one signal. Viewers can easily see how hepatalin levels greatly impact nutrient partitioning to fat and muscle cells, and understand the consequences to a patient's health. © 2021 SciMar Ltd.
The project
The discovery of hepatalin by Dr. Wayne Laut is poised to change type 2 diabetes care and prevention. Our client needed an accurate, easily-understood medical animation to explain the role of hepatalin and its implications to a wide-ranging audience. Glucose levels are regulated by a system of interconnected pathways; changing one signal can unbalance the entire system and result in diabetes. To simplify this complexity, we created a factory analogy in which a series of pipes and conveyor belts transport nerve signals, hormones, and nutrients between different organ “stations”. This allows viewers to easily see the downstream effects of changing one signal and gain a clear understanding of glucose metabolism and hepatalin’s role. This medical animation has become a key resource on SciMar’s website, on social media, and in presentations. Viewer’s have reported “lightbulb” moments, in which they can finally appreciate how tweaking just a few signals has the potential to combat, and potentially prevent, diabetes. To learn more about hepatalin, see this review in the Canadian Journal of Pharmacology and Physiology
Created for
Scimar Ltd.
![We’re excited to share that “Nanoparticle Delivery to a Solid Tumour” took home an Award of Excellence from the Association of Medical Illustrators (@amidotorg).
This 3D scientific animation was a collaboration between @axs_studio and the Integrated Nanotechnology and Biomedical Sciences (INBS) Laboratory, created to explain nanoparticle (NP) transport within a cancerous tumour microenvironment.
NPs have the potential to deliver therapeutic and diagnostic agents to tumours but a full understanding of their dynamics within the human body is essential to making the science a clinical reality for patients. That’s where INBS comes in.
INBS is a pioneer and global leader in nanotechnology, under the leadership of Prof. Warren Chan. Their active transport and retention (ATR) principle in Nature Nanotechnology (https://www.nature.com/articles/s41565-025-01877-5), challenged widely held beliefs about nanoparticle delivery to tumours.
AXS Studio collaborated with INBS scientists Matthew Nguyen and Jamie Wu on a concise scientific animation to explain this principle visually. Because scientific accuracy was essential, our medical animators consulted INBS’ extensive body of research data, including still and time-lapse micrographs, to accurately visualize the mechanisms governing NP tumor entry, retention, and exit. We also surveyed peer-reviewed sources on gross- and micro-anatomy to ensure accurate depiction of the tissue environments. The [finished video] is a captivating visualization of this groundbreaking INBS research.
The Association of Medical Illustrators is recognized as the premier global resource for promoting the power of visual media to advance scientific understanding, communication, education, and research.
#nanomedicine #medicalanimation #scientificanimation #cancer #science #healthcare #medicine #oncology #3danimation #axs3d #sciart](https://axs3d.com/wp-content/plugins/instagram-feed/img/placeholder.png)