![axs-studio-scientific-animation-cytoplasm-mitochondria](https://axs3d.com/wp-content/uploads/2024/03/axs-studio-medical-animation-light-therapy-amd-01-1024x576.jpg)
Medical Animation: Proteasome in Multiple Myeloma
Created for Biopharmaceutical client
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![axs-studio-medical-animation-mulitple-myeloma-proteasome](https://axs3d.com/wp-content/plugins/tia/img/bg-placeholder.jpg)
Detailed 3D rendering of the proteasome, a key macromolecular machine regulating cell health by degrading unwanted proteins. In this image, the enzymatic subunits of the proteasome are labelled: Chymotrypin-like (CT-L); Caspase-like (C-L); Trypsin-like (T-L). From a medical animation about the function of the proteasome in unwanted protein degradation. Myeloma cells exploit this function to survive under conditions of ER stress, via the unfolded protein response (UPR). © 2016. All Rights Reserved.
![axs-studio-medical-animation-mulitple-myeloma-ER-stress](https://axs3d.com/wp-content/plugins/tia/img/bg-placeholder.jpg)
ER stress. The accumulation of misfolded proteins in the endoplasmic reticulum results in ER stress that can lead eventually to cell death. From a medical animation about the function of the proteasome in unwanted protein degradation. Myeloma cells exploit this function to survive under conditions of ER stress, via the unfolded protein response (UPR). © 2016. All Rights Reserved.
![axs-studio-medical-animation-mulitple-myeloma-bone-lesions](https://axs3d.com/wp-content/plugins/tia/img/bg-placeholder.jpg)
Lytic bone lesions in multiple myeloma. From a medical animation about the function of the proteasome in unwanted protein degradation. Myeloma cells exploit this function to survive under conditions of ER stress, via the unfolded protein response (UPR). © 2016. All Rights Reserved.
The project
Our challenge in this medical animation was to present the proteasome as both a vital tool for healthy cells, and a key weapon of survival for cancer cells. We based our proteasome’s structure and function on data from peer reviewed literature. A warm palette and bright lighting underscore the idea that the proteasome is not a sinister force, but rather an innocuous player in a noxious process.
Created for
Biopharmaceutical client