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Illustration

Medical Illustration: Kidney Disease Progression in ADPKD

Created for Otsuka Pharmaceutical; BioScience Communications
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The project

In polycystic kidney disease, kidney function is linked to disease progression. We created this medical illustration to accurately portray physical disease progression in correlation with function, symptoms an other complications for an FDA Advisory Committee meeting.

Created for
Otsuka Pharmaceutical
BioScience Communications

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Illustration

Cyborg Tadpole cover for Nature Publishing Volume 642 Issue 8069, 26 June 2025

Scientific illustration

Nature Journal

Detail from a medical illustration for Scientific American article

Medical illustration

Scientific American Magazine

Illustrations for Human Virome article written by David Pride for the Scientific American December 2020 issue. 2D and 3D assets created by AXS. Final layout by Scientific American. Illustrates the the difference viruses found in the human virome, colour coded as orange if the virus is known to cause human illness.

Medical illustration

Scientific American Magazine

Double spread illustration comparing antibiotics vs phages and the evolution of resistant bacteria on left. Three types of phage therapy are explored on right panel.

Scientific illustration

Scientific American Magazine

3D illustration for Eupraxia's presentation deck, explaining how it's controlled-release drug delivery technology works. The illustration features a knee with osteoarthritis (OA), particles diffusing medication into the joint space and a closeup view of drug molecules diffusing from the crystal core, through the polymer shell.

Medical illustration: Analgesic Drug Delivery for Osteoarthritis

Eupraxia Pharmaceuticals Inc.

The illustration has 4 panels depicting certepetide's mechanism of action. Certepetide is a 9 amino acide cyclic peptide that is Lisata's investigational agent. The first panel in the illustration depicts certepetide binding to an integrin on tumor/tumor vascular endothelium. The second panel shows proteolytic cleavage of certepetide. The third panel depicts the resulting CendR fragment binding to neuropilin-1 (NRP1). Panel 4 depicts the resulting tumor penetration (CendR pathway activation involving microvesicles that encapsulate co-administered anti-cancer drugs).

Scientific illustration: Certepetide Anticancer MOA

Pharmaceutical client

MOA illustration showing immune suppresed tumor microenvironment at the top. Tumor cells overexpress CD200 and bind to CD200R1 on NK, CD8 and CD4 t-cells to inhibit DOK2/RasGap signaling and subsequent immune response. The bottom right of the illustration shows the reversal of immune suppression mediated by 23ME-0610 mAb binding to CD200R1 on immune cells and free up downnstream signaling. This reactivates the anti-tumor immune response.

Scientific illustration: Cancer Immunotherapy MOA

Pharmaceutical client

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Paying Homage to Nature's 10

Nature Magazine

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Microbiome Scientific Illustration for Nature

Nature

Inside spread (poster) of Immune Thrombocytic Purpura or ITP brochure with medical illustrations. Understanding the role of TPO or thrombopoietin in normal platelet formation. TPO binds TPO receptor on the megakaryocyte progenitor to induce proliferation and maturation into platelet producing megakaryocyte. Macrophages clear aged or damaged platelets. JAK-STAT pathway leads to platelet production. In ITP pathogenesis, immune system dysregulation via either autoantibody mediated pathway or cytotoxic t-cell mediate pathway, results in inbited platelet production and accelerated platelet destruction by macrophages.

Autoimmune Disease Medical Illustration

Biopharmaceutical client

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Cystic Fibrosis (CF) Scientific Illustration

Scientific American

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Scientific Illustration: CRISPR - A Revolution in Genetics

Scientific American

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We’re excited to share that “Nanoparticle Deli We’re excited to share that “Nanoparticle Delivery to a Solid Tumour” took home an Award of Excellence from the Association of Medical Illustrators (@amidotorg).

This 3D scientific animation was a collaboration between @axs_studio and the Integrated Nanotechnology and Biomedical Sciences (INBS) Laboratory, created to explain nanoparticle (NP) transport within a cancerous tumour microenvironment.

NPs have the potential to deliver therapeutic and diagnostic agents to tumours but a full understanding of their dynamics within the human body is essential to making the science a clinical reality for patients. That’s where INBS comes in.

INBS is a pioneer and global leader in nanotechnology, under the leadership of Prof. Warren Chan. Their active transport and retention (ATR) principle in Nature Nanotechnology (https://www.nature.com/articles/s41565-025-01877-5), challenged widely held beliefs about nanoparticle delivery to tumours.

AXS Studio collaborated with INBS scientists Matthew Nguyen and Jamie Wu on a concise scientific animation to explain this principle visually. Because scientific accuracy was essential, our medical animators consulted INBS’ extensive body of research data, including still and time-lapse micrographs, to accurately visualize the mechanisms governing NP tumor entry, retention, and exit. We also surveyed peer-reviewed sources on gross- and micro-anatomy to ensure accurate depiction of the tissue environments. The [finished video] is a captivating visualization of this groundbreaking INBS research.

The Association of Medical Illustrators is recognized as the premier global resource for promoting the power of visual media to advance scientific understanding, communication, education, and research.

#nanomedicine #medicalanimation #scientificanimation #cancer #science #healthcare #medicine #oncology #3danimation #axs3d #sciart
3rd Annual Medical Illustration Dog Show at the Gr 3rd Annual Medical Illustration Dog Show at the Grand Rapids Art Museum. Thanks to the sponsors @microverse_studios and @real.chemistry for a fantastic party and lots of laughs
The new @axs_studio show reel features our top med The new @axs_studio show reel features our top medical and scientific animation projects from the past few years. This compilation spans oncology, cardiology, dermatology, molecular biology, nanotechnology, neuroscience, ophthalmology, rare diseases, targeted drug delivery, robotic surgery and more. It's a must-see for professionals in healthcare, biopharma, medical affairs and scientific communications. Sound on for the excellent musical score by @zachkellum.
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#sciart #science #medicalanimation #sciencevisualization #animation #pharma
If you’ve ever studied pictures in a biology tex If you’ve ever studied pictures in a biology textbook or admired the posters in your doctor’s office and wondered “who makes these?”, our latest blog post, "What is a medical illustrator?", is for you: https://axs3d.com/blog/what-is-medical-illustrator/ 6-minute read.
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#medicalcommunications #medicalaffairs #sciart #medicalart #medicalanimation #scientificcommunication #scicomm #medcom #healthcommunication #pharma #amidotorg
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